About Enhancer
| Enhancer ID: | E_01960 |
| Species: | Mus musculus |
| Position : | chr6:50789172-50828639   |
| Year: | 2023 |
| Title: | A multiple super-enhancer region establishes inter-TAD interactions and controls Hoxa function in cranial neural crest. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 37277355 |
| Tissue: | pharyngeal arch |
| Tissue Ontology ID: | UBERON:0002539 |
| Cell Source: | Cranial neural crest cells |
| Cell Type: | cranial neural crest cell |
| Experiment Type: | Chromatin interaction assay, Functional perturbation assay, Enhancer activity assay, TF binding assay |
| High Throughput Method: | ChIP-seq; RNA-seq; Hi-C; ATAC-seq |
| Low Throughput Method: | CRISPR knockout; RT-RT-qPCR; Western blot |
About Target Gene
| Target gene : | Hoxa2 |
About TF
| TF name : | Hoxa2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Hoxa2 | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer