About Enhancer
| Enhancer ID: | E_01973 |
| Species: | Homo sapiens |
| Position : | chr19:61151074-61161722   |
| Year: | 2014 |
| Title: | Transcription Factor IRF8 Governs Enhancer Landscape Dynamics in Mononuclear Phagocyte Progenitors |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 29514092 |
| MONDO: | |
| Tissue: | Prostate |
| Tissue Ontology ID: | UBERON:0002367 |
| Cell Source: | |
| CVCL ID: | |
| Cell Type: | |
| Cell Ontology ID: | |
| Experiment Type: | Enhancer activity assay, TF binding assay |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | qRT-PCR, and ChIP-qPCR |
About Target Gene
| Target gene : | CSF2RA |
About TF
| TF name : | IRF8 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| IRF8 | GMCSF-mediated signaling events | pid | 38 |
| IRF8 | Interferon alpha/beta signaling | reactome | 67 |
| IRF8 | Interferon gamma signaling | reactome | 88 |
| IRF8 | Validated targets of C-MYC transcriptional repression | pid | 63 |
| IRF8 | Hs_Type_II_interferon_signaling_(IFNG)_WP619_71168 | wikipathways | 10 |
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer