Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01983
Species: Homo sapiens
Position : chr14:22553100-22553200
Year: 2025
Title: A pooled CRISPR screen identifies the T??2 enhancer element as a driver of TRA expression in a subset of mature human T lymphocytes
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  40160815
MONDO:
Tissue: Blood
Tissue Ontology ID: UBERON:0000178
Cell Source: primary human CD3+ T cells
CVCL ID:
Cell Type: T cell
Cell Ontology ID: CL:0000084
Experiment Type: Functional perturbation assay
High Throughput Method: CRISPR screen
Low Throughput Method: CRISPR Knockout, CRISPRi, RT-RT-qPCR, Flow Cytometry, Sanger Sequencing
About Target Gene
Target gene : TRAC
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 1 found
Enhancer ID Position Tissue Cell Disease
E_01984 chr14:22553100-22553200 Blood macrophage --
Expression of Target Genes for the Enhancer