About Enhancer
| Enhancer ID: | E_01984 |
| Species: | Homo sapiens |
| Position : | chr14:22553100-22553200   |
| Year: | 2025 |
| Title: | A pooled CRISPR screen identifies the T??2 enhancer element as a driver of TRA expression in a subset of mature human T lymphocytes |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 40160815 |
| MONDO: | |
| Tissue: | Blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Monocyte-derived macrophage (hMDM) |
| CVCL ID: | |
| Cell Type: | macrophage |
| Cell Ontology ID: | CL:0000235 |
| Experiment Type: | Functional perturbation assay |
| High Throughput Method: | CRISPR screen |
| Low Throughput Method: | CRISPR Knockout, CRISPRi, RT-RT-qPCR, Flow Cytometry, Sanger Sequencing |
About Target Gene
| Target gene : | TRAC |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01983 | chr14:22553100-22553200 | Blood | T cell | -- |
Expression of Target Genes for the Enhancer