About Enhancer
| Enhancer ID: | E_01989 |
| Species: | Mus musculus |
| Position : | chr5:29314497-29315844   |
| Year: | 2025 |
| Title: | Range extender mediates long-distance enhancer activity |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 40604280 |
| MONDO: | |
| Tissue: | Limb Bud |
| Tissue Ontology ID: | UBERON:0005417 |
| Cell Source: | Zone of polarizing activity cells |
| CVCL ID: | |
| Cell Type: | mesenchymal cell |
| Cell Ontology ID: | CL:0000134 |
| Experiment Type: | TF binding assay, Enhancer activity assay, Functional perturbation assay |
| High Throughput Method: | ATAC-seq, ChIP-seq, Hi-C, scATAC-seq/scRNA-seq multiome, RNA-seq |
| Low Throughput Method: | Transgenic Reporter Assay, CRISPR Knockout, CRISPR Knock-in, RT-RT-qPCR, Whole-mount in situ hybridization, Skeletal staining, EMSA, Luciferase Reporter Assay |
About Target Gene
| Target gene : | Shh |
About TF
| TF name : | Lhx2; Lhx9; Lef1; Ets1; Etv; Hox |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer