About Enhancer
| Enhancer ID: | E_01994 |
| Species: | Mus musculus |
| Position : | chr8:83274000-83275000   |
| Year: | 2025 |
| Title: | Identification of a distal enhancer of Ucp1 essential for thermogenesis and mitochondrial function in brown fat |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 39789228 |
| MONDO: | |
| Tissue: | Brown adipose tissue |
| Tissue Ontology ID: | UBERON:0001348 |
| Cell Source: | Brown adipocytes (SVF) |
| CVCL ID: | |
| Cell Type: | brown adipocyte |
| Cell Ontology ID: | CL:0000136 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | 4C-seq, ChIP-seq, ATAC-seq, RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay, CRISPRi, 3C-RT-qPCR, qRT-PCR, Western blot |
About Target Gene
| Target gene : | Ucp1 |
About TF
| TF name : | Ebf2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer