About Enhancer
| Enhancer ID: | E_02018 |
| Species: | Mus musculus |
| Position : | chr10:80245000-80246500   |
| Year: | 2018 |
| Title: | CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 30545847 |
| MONDO: | |
| Tissue: | Embryo |
| Tissue Ontology ID: | UBERON:0000922 |
| Cell Source: | Mouse Embryonic Stem Cells (mESCs; E14TG2a; J1) |
| CVCL ID: | CVCL_2167 |
| Cell Type: | mouse embryonic stem cell |
| Cell Ontology ID: | CL:0002322 |
| Experiment Type: | Functional perturbation assay, Enhancer activity assay |
| High Throughput Method: | ChIP-seq, ATAC-seq |
| Low Throughput Method: | CRISPR Activation, Luciferase Reporter Assay |
About Target Gene
| Target gene : | Sim1 |
About TF
| TF name : | Sim1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer