About Enhancer
| Enhancer ID: | E_02030 |
| Species: | Homo sapiens |
| Position : | chr17:44542500-44543500   |
| Year: | 2025 |
| Title: | Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 40997217 |
| Tissue: | zone of skin |
| Tissue Ontology ID: | UBERON:0000014 |
| Cell Source: | Human neonatal foreskin fibroblasts |
| Cell Type: | fibroblast |
| Cell Ontology ID: | CL:0000057 |
| Experiment Type: | CRISPR interference-based functional screen; Endogenous enhancer perturbation |
| High Throughput Method: | ATAC-seq, RNA-seq, HiCAR, CRISPRi screening, single-cell RNA-seq; single-cell RNA-seq; RNA-seq |
| Low Throughput Method: | Luciferase reporter assay, RT-qPCR, flow cytometry; CRISPR-Cas9 endogenous deletion/editing |
About Target Gene
| Target gene : | FZD2 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer