About Enhancer
| Enhancer ID: | E_02035 |
| Species: | Mus musculus |
| Position : | chr6:50789172-50828639   |
| Year: | 2023 |
| Title: | A multiple super-enhancer region establishes inter-TAD interactions and controls Hoxa function in cranial neural crest |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 37277355 |
| MONDO: | |
| Tissue: | Craniofacial Tissue |
| Tissue Ontology ID: | UBERON:0010368 |
| Cell Source: | Primary cranial neural crest cells |
| CVCL ID: | |
| Cell Type: | cranial neural crest cell |
| Cell Ontology ID: | CL:0000333 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq, Hi-C, ATAC-seq, PCHi-C |
| Low Throughput Method: | CRISPR Knockout, RT-RT-qPCR, Whole-mount in situ hybridization, Skeletal staining |
About Target Gene
| Target gene : | H3K27Ac |
About TF
| TF name : | Hoxa2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Hoxa2 | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
3 found
Expression of Target Genes for the Enhancer