About Enhancer
| Enhancer ID: | E_02045 |
| Species: | Mus musculus |
| Position : | chr14:53397365-53398765   |
| Year: | 2019 |
| Title: | Esrrb function is required for proper primordial germ cell development in presomite stage mouse embryos |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 31301373 |
| MONDO: | |
| Tissue: | Spleen |
| Tissue Ontology ID: | UBERON:0002106 |
| Cell Source: | Bone Marrow-Derived Macrophages |
| CVCL ID: | |
| Cell Type: | macrophage |
| Cell Ontology ID: | CL:0000235 |
| Experiment Type: | Enhancer activity assay, TF binding assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay, CRISPR Knockout, RT-RT-qPCR |
About Target Gene
| Target gene : | Bmp4 |
About TF
| TF name : | Esrrb |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Esrrb | Nuclear Receptor transcription pathway | reactome | 51 |
| Esrrb | Hs_Wnt_Signaling_Pathway_and_Pluripotency_WP399_90291 | wikipathways | 12 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer