Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02049
Species: Mus musculus
Position : chr7:3198900-3202780
Year: 2019
Title: Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  31422875
MONDO:
Tissue: Embryo
Tissue Ontology ID: UBERON:0000922
Cell Source: Epiblast-like Cells (EpiLCs)
CVCL ID:
Cell Type: epiblast-like cell
Cell Ontology ID: CL:0002322
Experiment Type: Enhancer activity assay, TF binding assay, Functional perturbation assay
High Throughput Method: ChIP-seq, RNA-seq, WGBS, Hi-C
Low Throughput Method: Transgenic Reporter Assay (RGM), CRISPR Knockout, ChIP-RT-qPCR, RT-RT-qPCR, DNA FISH, Immunofluorescence, Confocal Imaging
About Target Gene
Target gene : Mir290-295
About TF
TF name : Pou5F1; Nanog
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 1 found
Enhancer ID Position Tissue Cell Disease
E_02048 chr7:3198900-3202780 Embryo mouse embryonic stem cell --
Expression of Target Genes for the Enhancer