About Enhancer
| Enhancer ID: | E_02055 |
| Species: | Mus musculus |
| Position : | chr6:113000000-113001000   |
| Year: | 2025 |
| Title: | Rewiring of SINE-MIR enhancer topology and Esrrb modulation in expanded and naive pluripotency |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 40296153 |
| MONDO: | |
| Tissue: | Blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | RAW264.7 |
| CVCL ID: | CVCL_0493 |
| Cell Type: | macrophage |
| Cell Ontology ID: | CL:0000235 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | Hi-C, HiChIP, RNA-seq, ChIP-seq |
| Low Throughput Method: | CRISPR knockout, ChIP-RT-qPCR, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | Klf5 |
About TF
| TF name : | Esrrb |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Esrrb | Nuclear Receptor transcription pathway | reactome | 51 |
| Esrrb | Hs_Wnt_Signaling_Pathway_and_Pluripotency_WP399_90291 | wikipathways | 12 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer