Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02080
Species: Mus musculus
Position : chr17:35600000-35630000
Year: 2015
Title: Convergence of developmental and oncogenic signaling pathways at transcriptional super-enhancers
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  25801169
MONDO:
Tissue: Embryo
Tissue Ontology ID: UBERON:0000922
Cell Source: mouse ESCs
CVCL ID:
Cell Type: mouse embryonic stem cell
Cell Ontology ID: CL:0002322
Experiment Type: Enhancer activity assay, Functional perturbation assay
High Throughput Method: ChIP-seq, RNA-seq
Low Throughput Method: Luciferase Reporter Assay, CRISPR Knockout
About Target Gene
Target gene : Pou5F1
About TF
TF name : Oct4; Sox2; Nanog
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 3 found
Enhancer ID Position Tissue Cell Disease
E_03074 chr17:33930235-37702617 Colon colorectal cancer cell colorectal cancer
E_02464 chr17:35602100-35602600 Embryo mouse embryonic stem cell --
E_02866 chr17:35605300-35605800 Embryo mouse embryonic stem cell --
Expression of Target Genes for the Enhancer