Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02086
Species: Mus musculus
Position : chr1:180924460-180925486
Year: 2024
Title: The cells are all-right: Regulation of the Lefty genes by separate enhancers in mouse embryonic stem cells
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  39671433
MONDO:
Tissue: Embryo
Tissue Ontology ID: UBERON:0000922
Cell Source: Mouse embryonic stem
CVCL ID:
Cell Type: mouse embryonic stem cell
Cell Ontology ID: CL:0002322
Experiment Type: Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay
High Throughput Method: ChIP-seq, RNA-seq, Hi-C
Low Throughput Method: CRISPR Knockout, RT-RT-qPCR
About Target Gene
Target gene : Lefty1
About TF
TF name : Sox2; Nanog; Klf4; Esrrb; Zfx; E2F1; Tfcp2I1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer