About Enhancer
| Enhancer ID: | E_02098 |
| Species: | Mus musculus |
| Position : | chr17:63643401-63643706   |
| Year: | 2022 |
| Title: | Hnf1b renal expression directed by a distal enhancer responsive to Pax8 |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 36402859 |
| MONDO: | |
| Tissue: | Kidney |
| Tissue Ontology ID: | UBERON:0002113 |
| Cell Source: | MDCK |
| CVCL ID: | CVCL_0422 |
| Cell Type: | kidney epithelial cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | ATAC-seq, ChIP-seq, DNase-seq |
| Low Throughput Method: | Luciferase Reporter Assay, Transgenic Reporter Assay, CRISPR Knockout, EMSA |
About Target Gene
| Target gene : | Hnf1B |
About TF
| TF name : | Pax8 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Pax8 | ID | netpath | 38 |
| Pax8 | Pathways in cancer | kegg | 321 |
| Pax8 | Thyroid cancer | kegg | 25 |
| Pax8 | Hs_Thyroid_Stimulating_Hormone_(TSH)_signaling_pathway_WP2032_89823 | wikipathways | 28 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02099 | chr17:63643401-63643706 | Kidney | kidney epithelial cell | -- |
Expression of Target Genes for the Enhancer