Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02113
Species: Homo sapiens
Position : chr8:128556059-128557653
Year: 2022
Title: Targeting of noncoding RNAs encoded by a novel MYC enhancers inhibits the proliferation of human hepatic carcinoma cells in vitro.
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
Disease Name: hepatocellular carcinoma
PMID:  35039581
MONDO: MONDO:0007256
Tissue: liver
Tissue Ontology ID: UBERON:0002107
Cell Source: Hep-G2
CVCL ID: CVCL_0027
Cell Type: malignant cell
Cell Ontology ID: CL:0001064
Experiment Type: Enhancer activity assay, Functional perturbation assay; Enhancer activity assay; Endogenous enhancer perturbation
High Throughput Method: ChIP-seq, GRO-seq
Low Throughput Method: Luciferase Reporter Assay, CRISPR Knockout, qRT-PCR; CRISPR-Cas9 endogenous deletion/editing; Reporter assay
About Target Gene
Target gene : MYC
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 1 found
Enhancer ID Position Tissue Cell Disease
E_03876 chr8:126650000-129950000 colon malignant cell NA
Expression of Target Genes for the Enhancer