About Enhancer
| Enhancer ID: | E_02118 |
| Species: | Mus musculus |
| Position : | chr8:123455000-123472000   |
| Year: | 2020 |
| Title: | Super-enhancer-driven metabolic reprogramming promotes cystogenesis in autosomal dominant polycystic kidney disease |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | polycystic kidney disease |
| PMID: | 32694829 |
| MONDO: | MONDO:0005290 |
| Tissue: | Kidney |
| Tissue Ontology ID: | UBERON:0002113 |
| Cell Source: | Pkd1-null tubule epithelial cells (PN) |
| CVCL ID: | |
| Cell Type: | kidney epithelial cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Functional perturbation assay, Enhancer activity assay |
| High Throughput Method: | ChIP-seq, RNA-seq, ATAC-seq |
| Low Throughput Method: | ChIP-RT-qPCR, RT-RT-qPCR, Western blot, CRISPR Knockout, Flow Cytometry, Immunohistochemistry, HPLC |
About Target Gene
| Target gene : | Ampd3 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer