Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02119
Species: Mus musculus
Position : chr8:123455000-123472000
Year: 2020
Title: Super-enhancer-driven metabolic reprogramming promotes cystogenesis in autosomal dominant polycystic kidney disease
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  32694829
MONDO:
Tissue: Kidney
Tissue Ontology ID: UBERON:0002113
Cell Source: Pkd1-heterozygous control tubule epithelial cells (PH)
CVCL ID:
Cell Type: kidney epithelial cell
Cell Ontology ID: CL:0000066
Experiment Type: Functional perturbation assay, Enhancer activity assay
High Throughput Method: ChIP-seq, RNA-seq, ATAC-seq
Low Throughput Method: ChIP-RT-qPCR, RT-RT-qPCR, Western blot, CRISPR Knockout, Flow Cytometry, Immunohistochemistry, HPLC
About Target Gene
Target gene : Ampd3
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 2 found
Enhancer ID Position Tissue Cell Disease
E_02118 chr8:123455000-123472000 Kidney kidney epithelial cell polycystic kidney disease
E_02120 chr8:123455000-123472000 Kidney renal tubular epithelial cell --
Expression of Target Genes for the Enhancer