Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02122
Species: Homo sapiens
Position : chrX:49260470-49261090
Year: 2026
Title: FOXP3 expression depends on cell-type-specific cis-regulatory elements and transcription factor circuitry.
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Normal
PMID:  41237776
Tissue: blood
Tissue Ontology ID: UBERON:0000178
Cell Source: Primary regulatory T cells
Cell Type: regulatory T cell
Cell Ontology ID: CL:0000815
Experiment Type: Enhancer activity assay; Functional perturbation assay
High Throughput Method: Pooled CRISPRi locus-tiling screen; ATAC-seq; H3K27ac ChIP-seq; PBAT-seq
Low Throughput Method: FOXP3 flow cytometry; targeted bisulfite sequencing
About Target Gene
Target gene : FOXP3
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 2 found
Enhancer ID Position Tissue Cell Disease
E_02123 chrX:49260470-49261090 NA NA NA
E_03065 chrX:49260470-49261090 blood regulatory T cell NA
Expression of Target Genes for the Enhancer