Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02134
Species: Mus musculus
Position : chr15:103026344-103028143
Year: 2021
Title: Chromatin accessibility landscape of cardiac pacemaker cells defines an Isl1 enhancer required for sinoatrial node development and function
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  34335313
MONDO:
Tissue: Heart
Tissue Ontology ID: UBERON:0000948
Cell Source: Sinoatrial Node Pacemaker
CVCL ID:
Cell Type: sinoatrial node pacemaker cell
Cell Ontology ID: CL:0000746
Experiment Type: Enhancer activity assay, Functional perturbation assay
High Throughput Method: ATAC-seq, RNA-seq, ChIP-seq
Low Throughput Method: Transgenic Reporter Assay, CRISPR Knockout, X-gal Staining
About Target Gene
Target gene : Hcn4
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 1 found
Enhancer ID Position Tissue Cell Disease
E_02975 chr15:103026344-103028143 Heart cardiomyocyte --
Expression of Target Genes for the Enhancer