About Enhancer
| Enhancer ID: | E_02136 |
| Species: | Mus musculus |
| Position : | chr7:142599494-142601493   |
| Year: | 2025 |
| Title: | Igf2 adult-specific skeletal muscle enhancer activity revealed in mice with intergenic CTCF boundary deletion |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 40880432 |
| MONDO: | |
| Tissue: | Skeletal muscle |
| Tissue Ontology ID: | UBERON:0001134 |
| Cell Source: | Skeletal muscle myocytes |
| CVCL ID: | |
| Cell Type: | skeletal muscle myocyte |
| Cell Ontology ID: | CL:0000187 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | Capture-C, ChIP-seq, ATAC-seq, RNA-seq |
| Low Throughput Method: | CRISPR Knockout, qRT-PCR, Southern Blot |
About Target Gene
| Target gene : | Igf2 |
About TF
| TF name : | Myod1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Myod1 | C-MYB transcription factor network | pid | 87 |
| Myod1 | CDO in myogenesis | reactome | 29 |
| Myod1 | ID | netpath | 38 |
| Myod1 | Notch-mediated HES/HEY network | pid | 48 |
| Myod1 | Regulation of nuclear SMAD2/3 signaling | pid | 82 |
| Myod1 | Regulation of retinoblastoma protein | pid | 67 |
| Myod1 | Signaling events mediated by HDAC Class III | pid | 41 |
| Myod1 | Hs_ID_signaling_pathway_WP53_67360 | wikipathways | 8 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer