About Enhancer
| Enhancer ID: | E_02151 |
| Species: | Homo sapiens |
| Position : | chr16:54926631-54929466   |
| Year: | 2024 |
| Title: | Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | T-cell acute lymphoblastic leukemia |
| PMID: | 39316719 |
| MONDO: | MONDO:0004963 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | ALL-SIL |
| CVCL ID: | CVCL_1805 |
| Cell Type: | T-cell |
| Experiment Type: | Enhancer activity assay; Functional perturbation assay; Chromatin interaction assay; Chromatin accessibility assay; Histone modification profiling |
| High Throughput Method: | H3K27ac HiChIP; H3K27ac ChIP-seq; ATAC-seq; RNA-seq |
| Low Throughput Method: | CRISPR/Cas9 deletion; UMI-4C; qRT-PCR |
About Target Gene
| Target gene : | IRX3 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer