About Enhancer
| Enhancer ID: | E_02185 |
| Species: | Mus musculus |
| Position : | chr2:169760000-169760653   |
| Year: | 2023 |
| Title: | An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 37552875 |
| MONDO: | |
| Tissue: | Pancreas |
| Tissue Ontology ID: | UBERON:0001264 |
| Cell Source: | Pancreatic islet cells |
| CVCL ID: | |
| Cell Type: | pancreatic islet cell |
| Cell Ontology ID: | CL:0000168 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | ATAC-seq, RNA-seq |
| Low Throughput Method: | CRISPR Knockout, Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | G6Pc2 |
About TF
| TF name : | Mafb |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Mafb | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| Mafb | Hs_Ectoderm_Differentiation_WP2858_89329 | wikipathways | 56 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer