Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02190
Species: Mus musculus
Position : chr2:11656369-11660078
Year: 2023
Title: Distinct use of super-enhancer elements controls cell type-specific CD25 transcription and function
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  37922339
MONDO:
Tissue: Spleen
Tissue Ontology ID: UBERON:0002106
Cell Source: CD8+ T
CVCL ID:
Cell Type: CD8-positive T cell
Cell Ontology ID: CL:0000625
Experiment Type: Regulatory element functional validation, 3D chromatin interaction mapping
High Throughput Method: ChIP-seq, HiChIP, RNA-seq
Low Throughput Method: CRISPR-Cas9 deletion, flow cytometry, reporter assay
About Target Gene
Target gene : Il2Ra
About TF
TF name : Stat5
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer