About Enhancer
| Enhancer ID: | E_02192 |
| Species: | Mus musculus |
| Position : | chr8:57331591-57335031   |
| Year: | 2023 |
| Title: | The NR2F2-HAND2 signaling axis regulates progesterone actions in the uterus at early pregnancy |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 37664846 |
| MONDO: | |
| Tissue: | Uterus |
| Tissue Ontology ID: | UBERON:0000995 |
| Cell Source: | Uterine stromal cells |
| CVCL ID: | |
| Cell Type: | endometrial stromal cell |
| Cell Ontology ID: | CL:0002255 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | ChIP-RT-qPCR, CRISPR Activation (CRISPRa), qRT-PCR, Western blot |
About Target Gene
| Target gene : | Hand2 |
About TF
| TF name : | Nr2F2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Nr2F2 | FOXA1 transcription factor network | pid | 45 |
| Nr2F2 | Regulation of Telomerase | pid | 70 |
| Nr2F2 | Transcriptional regulation of white adipocyte differentiation | reactome | 79 |
| Nr2F2 | Hs_White_fat_cell_differentiation_WP3946_90940 | wikipathways | 30 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer