Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02199
Species: Mus musculus
Position : chr8:32199690-32200290
Year: 2023
Title: Epigenetic regulation of Neuregulin 1 promotes breast cancer progression associated to hyperglycemia
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Disease
Disease Name: breast cancer
PMID:  36707514
MONDO: MONDO:0006120
Tissue: Mammary gland
Tissue Ontology ID: UBERON:0001911
Cell Source: Met1
CVCL ID: CVCL_UP55
Cell Type: breast carcinoma cell
Cell Ontology ID: CL:0000646
Experiment Type: Enhancer activity assay, TF binding assay, Functional perturbation assay
High Throughput Method: FAIRE-seq, RNA-seq
Low Throughput Method: Luciferase Reporter Assay, ChIP-RT-qPCR, CRISPR Knockout, qRT-PCR, Western blot
About Target Gene
Target gene : Nrg1
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer