Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02200
Species: Mus musculus
Position : chr11:10077283-10077800
Year: 2020
Title: The interdependence of mammary-specific super-enhancers and their native promoters facilitates gene activation during pregnancy
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  32321991
MONDO:
Tissue: Mammary Gland
Tissue Ontology ID: UBERON:0001911
Cell Source: Primary Mouse Mammary Epithelial
CVCL ID:
Cell Type: mouse mammary epithelial cell
Cell Ontology ID: CL:0000066
Experiment Type: Enhancer activity assay, TF binding assay, Functional perturbation assay
High Throughput Method: ChIP-seq, RNA-seq
Low Throughput Method: CRISPR Knockout, CRISPRi, RT-RT-qPCR
About Target Gene
Target gene : Wap
About TF
TF name : Stat5; Nfib; Nr3C1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 1 found
Enhancer ID Position Tissue Cell Disease
E_02202 chr11:10070908-10082508 Mammary Gland mouse mammary epithelial cell --
Expression of Target Genes for the Enhancer