Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02256
Species: Homo sapiens
Position : chr6:135418600-135418700
Year: 2016
Title: Dissection of the Major Hematopoietic Quantitative Trait Locus in Chromosome 6q23.3 Identifies miR-3662 as a Player in Hematopoiesis and Acute Myeloid Leukemia.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: acute myeloid leukemia
PMID:  27354268
MONDO: MONDO:0018874
Tissue: blood
Tissue Ontology ID: UBERON:0000178
Cell Source: Kasumi-1
CVCL ID: CVCL_0589
Experiment Type: Functional perturbation assay; Endogenous enhancer perturbation; Disease-variant functional analysis; In vivo functional validation
High Throughput Method: GWAS
Low Throughput Method: CRISPR/Cas9 genome editing; RT-qPCR; CRISPR-Cas9 endogenous deletion/editing; In vivo phenotyping
About Target Gene
Target gene : MIR3662
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_02181 chr6:135418600-135418700 bone marrow malignant cell acute myeloid leukemia
E_02264 chr6:135418600-135418700 NA hematopoietic progenitor cell NA
Expression of Target Genes for the Enhancer