Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02260
Species: Homo sapiens
Position : chr20:20392790-20394473
Year: 2025
Title: NKX2-1 drives neuroendocrine transdifferentiation of prostate cancer via epigenetic and 3D chromatin remodeling.
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
Disease Name: neuroendocrine prostate cancer
PMID:  40691407
MONDO: MONDO:0002477
Tissue: cervical lymph node
Tissue Ontology ID: UBERON:0002429
Cell Source: NCI-H660
CVCL ID: CVCL_1576
Cell Type: malignant cell
Cell Ontology ID: CL:0001064
Experiment Type: Chromatin interaction assay; Regulatory element annotation
High Throughput Method: Hi-C; H3K27ac ChIP-seq; H3K27me3 ChIP-seq; RNA-seq
Low Throughput Method: 3C
About Target Gene
Target gene : INSM1
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer