About Enhancer
| Enhancer ID: | E_02261 |
| Species: | Homo sapiens |
| Position : | chr5:44385797-44386845   |
| Year: | 2012 |
| Title: | ISL1 directly regulates FGF10 transcription during human cardiac outflow formation. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 22303449 |
| Tissue: | outflow tract |
| Tissue Ontology ID: | UBERON:0004145 |
| Cell Source: | C3H/10T1/2 clone 8 |
| CVCL ID: | CVCL_0190 |
| Cell Type: | fibroblast |
| Cell Ontology ID: | CL:0000057 |
| Experiment Type: | Enhancer activity assay |
| Low Throughput Method: | Dual-luciferase reporter assay;transcription-factor co-transfection;transgenic mouse LacZ reporter assay |
About Target Gene
| Target gene : | FGF10 |
About TF
| TF name : | TBX20 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| TBX20 | Hs_Heart_Development_WP1591_90186 | wikipathways | 28 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
8 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02257 | chr5:44385749-44386845 | heart | NA | NA |
| E_02258 | chr5:44385749-44386845 | heart | NA | NA |
| E_02259 | chr5:44385749-44386845 | heart | NA | NA |
| E_02235 | chr5:44385797-44386845 | outflow tract | fibroblast | NA |
| E_02243 | chr5:44385797-44386845 | outflow tract | cardiac progenitor cell | NA |
| E_02244 | chr5:44385797-44386845 | outflow tract | cardiac progenitor cell | NA |
| E_02278 | chr5:44385797-44386845 | outflow tract | fibroblast | NA |
| E_02279 | chr5:44385797-44386845 | outflow tract | fibroblast | NA |
Expression of Target Genes for the Enhancer