About Enhancer
| Enhancer ID: | E_02275 |
| Species: | Mus musculus |
| Position : | chr12:117170000-117198000   |
| Year: | 2022 |
| Title: | XLID syndrome gene Med12 promotes Ig isotype switching through chromatin modification and enhancer RNA regulation |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 36427307 |
| MONDO: | |
| Tissue: | Spleen |
| Tissue Ontology ID: | UBERON:0002106 |
| Cell Source: | CH12F3-2A |
| CVCL ID: | CVCL_7161 |
| Cell Type: | B cell |
| Cell Ontology ID: | CL:0000945 |
| Experiment Type: | Regulatory element functional validation, super-enhancer activation analysis |
| High Throughput Method: | |
| Low Throughput Method: | CRISPR-dCas9 enhancer activation, siRNA knockdown, ASO-mediated eRNA knockdown, 3C assay, ChIP-RT-qPCR, RT-RT-qPCR, flow cytometry |
About Target Gene
| Target gene : | Igh |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer