About Enhancer
| Enhancer ID: | E_02276 |
| Species: | Mus musculus |
| Position : | chr7:94261534-94261892   |
| Year: | 2019 |
| Title: | Differential transactivation of the upstream aggrecan enhancer regulated by PAX1/9 depends on SOX9-driven transactivation |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 30872687 |
| MONDO: | |
| Tissue: | Intervertebral disc |
| Tissue Ontology ID: | UBERON:0001066 |
| Cell Source: | Annulus fibrosus |
| CVCL ID: | |
| Cell Type: | annulus fibrosus cell |
| Cell Ontology ID: | CL:0000060 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay, CRISPR Knockout, ChIP-RT-qPCR, EMSA, RT-RT-qPCR, Co-immunoprecipitation, Transgenic Reporter Assay |
About Target Gene
| Target gene : | Acan |
About TF
| TF name : | Pax1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer