Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02288
Species: Mus musculus
Position : chr5:29314591-29316266
Year: 2022
Title: Etv2 regulates enhancer chromatin status to initiate Shh expression in the limb bud
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  35864091
MONDO:
Tissue: Limb bud
Tissue Ontology ID: UBERON:0005417
Cell Source: Embryonic limb mesenchyme
CVCL ID:
Cell Type: limb mesenchyme cell
Cell Ontology ID: CL:0000134
Experiment Type: Enhancer activity assay, TF binding assay, Chromatin interaction assay
High Throughput Method: ATAC-seq, ChIP-seq
Low Throughput Method: Luciferase Reporter Assay, ChIP-RT-qPCR, EMSA
About Target Gene
Target gene : Shh
About TF
TF name : Etv2
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 3 found
Enhancer ID Position Tissue Cell Disease
E_01989 chr5:29314497-29315844 Limb Bud mesenchymal cell --
E_01990 chr5:29314497-29315844 Bone Marrow myeloid progenitor cell --
E_02316 chr5:29314881-29315667 Limb Bud mesenchymal cell --
Expression of Target Genes for the Enhancer