About Enhancer
| Enhancer ID: | E_02289 |
| Species: | Homo sapiens |
| Position : | chr8:128748243-128748308   |
| Year: | 2022 |
| Title: | A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | malignant glioma |
| PMID: | 36201590 |
| MONDO: | MONDO:0100342 |
| Tissue: | brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | Neural stem |
| Cell Type: | neural stem cell |
| Cell Ontology ID: | CL:0000047 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay; Disease-variant functional analysis |
| High Throughput Method: | RNA-seq, GAM, 4C-seq |
| Low Throughput Method: | Transgenic Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR, Western blot, Immunofluorescence |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04572 | chr8:128747315-128748315 | colon | NA | colorectal cancer |
Expression of Target Genes for the Enhancer