About Enhancer
| Enhancer ID: | E_02294 |
| Species: | Homo sapiens |
| Position : | chr16:47657923-47659423   |
| Year: | 2019 |
| Title: | A novel enhancer RNA, Hmrhl, positively regulates its host gene, phkb, in chronic myelogenous leukemia. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | chronic myeloid leukemia |
| PMID: | 31891018 |
| MONDO: | MONDO:0011996 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | K-562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay; Enhancer activity assay |
| High Throughput Method: | ChIP-seq, ChIA-PET |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR, Western blot; Luciferase reporter assay; ChIP-qPCR; ChIP; siRNA knockdown |
About Target Gene
| Target gene : | PHKB |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02374 | chr16:47658623-47659423 | blood | malignant cell | chronic myeloid leukemia |
Expression of Target Genes for the Enhancer