About Enhancer
| Enhancer ID: | E_02294 |
| Species: | Mus musculus |
| Position : | chr2:9881939-9882773   |
| Year: | 2018 |
| Title: | Identification of Novel Gata3 Distal Enhancers Active in Mouse Embryonic Lens |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 30295986 |
| MONDO: | |
| Tissue: | Lens |
| Tissue Ontology ID: | UBERON:0000965 |
| Cell Source: | Lens epithelial cells |
| CVCL ID: | |
| Cell Type: | lens epithelial cell |
| Cell Ontology ID: | CL:0002224 |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | Luciferase Reporter Assay, Transgenic Reporter Assay, RT-RT-qPCR |
About Target Gene
| Target gene : | Gata3 |
About TF
| TF name : | Gata3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Gata3 | C-MYB transcription factor network | pid | 87 |
| Gata3 | Calcineurin-regulated NFAT-dependent transcription in lymphocytes | pid | 50 |
| Gata3 | Factors involved in megakaryocyte development and platelet production | reactome | 111 |
| Gata3 | Glucocorticoid receptor regulatory network | pid | 85 |
| Gata3 | IL27-mediated signaling events | pid | 26 |
| Gata3 | Notch signaling pathway | pid | 58 |
| Gata3 | Regulation of nuclear SMAD2/3 signaling | pid | 82 |
| Gata3 | Hs_Endochondral_Ossification_WP474_87977 | wikipathways | 43 |
| Gata3 | Hs_White_fat_cell_differentiation_WP3946_90940 | wikipathways | 30 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer