About Enhancer
| Enhancer ID: | E_02299 |
| Species: | Homo sapiens |
| Position : | chr8:128840000-128890000   |
| Year: | 2023 |
| Title: | SMARCB1 loss activates patient-specific distal oncogenic enhancers in malignant rhabdoid tumors. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | rhabdoid tumor |
| PMID: | 38040699 |
| MONDO: | MONDO:0002728 |
| Tissue: | kidney |
| Tissue Ontology ID: | UBERON:0002113 |
| Cell Source: | MRT patient-derived organoids (P103) |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Chromatin interaction assay, Enhancer activity assay, TF binding assay, Functional perturbation assay; Chromatin-state profiling |
| High Throughput Method: | Hi-C, 3C-seq, ATAC-seq, ChIP-seq, RNA-seq; single-cell RNA-seq; RNA-seq; ATAC-seq |
| Low Throughput Method: | 3C-RT-qPCR, qRT-PCR, Western blot |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_03876 | chr8:126650000-129950000 | colon | malignant cell | NA |
Expression of Target Genes for the Enhancer