About Enhancer
| Enhancer ID: | E_02303 |
| Species: | Mus musculus |
| Position : | chr8:124380000-124380454   |
| Year: | 2019 |
| Title: | An Nfil3-Zeb2-Id2 pathway imposes Irf8 enhancer switching during cDC1 development |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 31406377 |
| MONDO: | |
| Tissue: | Bone Marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | Pre-cDC1 |
| CVCL ID: | |
| Cell Type: | conventional dendritic cell |
| Cell Ontology ID: | CL:0000451 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | ATAC-seq, ChIP-seq, RNA-seq, scRNA-seq |
| Low Throughput Method: | Retroviral Reporter Assay, Site-directed Mutagenesis, RT-RT-qPCR, Flow Cytometry |
About Target Gene
| Target gene : | Irf8 |
About TF
| TF name : | E2A; Tcf4 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer