Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02314
Species: Mus musculus
Position : chr16:95721049-95979933
Year: 2025
Title: The Ets2 super-enhancer modulates endothelial-mesenchymal transition during cardiac aging
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  41253710
MONDO:
Tissue: Heart
Tissue Ontology ID: UBERON:0000948
Cell Source: Aortic endothelial cells
CVCL ID:
Cell Type: aortic endothelial cell
Cell Ontology ID: CL:0002546
Experiment Type: Functional perturbation assay
High Throughput Method: RNA-seq, ATAC-seq
Low Throughput Method: CRISPR knockout, RT-RT-qPCR, Western blot
About Target Gene
Target gene : Ets2
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 4 found
Enhancer ID Position Tissue Cell Disease
E_02313 chr16:95721049-95979933 Heart endothelial cell --
E_02144 chr16:95745432-95912361 Heart cardiomyocyte --
E_02145 chr16:95847911-95849564 Embryonic Limb Bud mesenchymal cell --
E_02146 chr16:95847911-95849564 Limb Bud mesenchymal cell --
Expression of Target Genes for the Enhancer