About Enhancer
| Enhancer ID: | E_02411 |
| Species: | Homo sapiens |
| Position : | chr16:1600000-1600110   |
| Year: | 2000 |
| Title: | Loading of DNA-binding factors to an erythroid enhancer. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 10688646 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | K-562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay; Endogenous enhancer perturbation; TF binding assay; In vivo functional validation |
| Low Throughput Method: | Luciferase Reporter Assay, RT-RT-qPCR, EMSA; ChIP; Site-directed/motif mutagenesis; In vivo phenotyping |
About Target Gene
| Target gene : | HBA1 |
About TF
| TF name : | NFE2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| NFE2 | Factors involved in megakaryocyte development and platelet production | reactome | 111 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer