About Enhancer
| Enhancer ID: | E_02440 |
| Species: | Homo sapiens |
| Position : | chr11:33944788-33945188   |
| Year: | 2019 |
| Title: | Global Analysis of Enhancer Targets Reveals Convergent Enhancer-Driven Regulatory Modules. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 31775028 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | K-562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Multiplex endogenous enhancer perturbation with single-cell transcriptomic target mapping; Disease-variant functional analysis |
| High Throughput Method: | Mosaic-seq pooled dCas9-KRAB CRISPRi; single-cell RNA-seq; DNase/H3K4me1/p300 regulatory-element integration |
| Low Throughput Method: | Bulk CRISPRi/RNA-seq or qRT-PCR validation for selected enhancers; pair-specific primary evidence is Mosaic-seq |
About Target Gene
| Target gene : | NAT10 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer