Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02446
Species: Homo sapiens
Position : chr2:226998914-227004586
Year: 2017
Title: Characterization of enhancers and the role of the transcription factor KLF7 in regulating corneal epithelial differentiation.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
PMID:  28916725
Cell Source: Human Corneal Epithelial Cells
Experiment Type: Enhancer activity assay; TF-binding/chromatin assay; Chromatin interaction assay; Genetic-variant functional analysis
High Throughput Method: ChIP-seq; ChIA-PET
Low Throughput Method: Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; RNAi/siRNA/shRNA
About Target Gene
Target gene : IRS1
About TF
TF name : EHF
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
EHF PDGF signaling pathway panther 113
Enhancer Associated Network
Overlapping Enhancers (hg19) 3 found
Enhancer ID Position Tissue Cell Disease
E_02426 chr2:226998914-227004586 cornea corneal epithelial cell NA
E_02403 chr2:226999986-227001986 cornea corneal epithelial cell corneal astigmatism
E_02423 chr2:227000886-227001086 cornea corneal epithelial cell astigmatism
Expression of Target Genes for the Enhancer