Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02455
Species: Homo sapiens
Position : chr6:31092587-31094587
Year: 2017
Title: Characterization of enhancers and the role of the transcription factor KLF7 in regulating corneal epithelial differentiation.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
PMID:  28916725
Tissue: cornea
Tissue Ontology ID: UBERON:0000964
Cell Source: primary human corneal epithelial cells
Cell Type: corneal epithelial cell
Cell Ontology ID: CL:0000575
Experiment Type: Enhancer profiling; Enhancer activity assay; Chromatin-state profiling; Disease-variant functional analysis
High Throughput Method: H3K4me1 ChIP-seq; H3K27ac ChIP-seq; H3K4me3 ChIP-seq; ChIP-seq
Low Throughput Method: Luciferase reporter assay; ChIP
About Target Gene
Target gene : PSORS1C1
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_02452 chr6:31092587-31094587 cornea corneal epithelial cell Stevens-Johnson syndrome-associated corneal phenotype
E_02459 chr6:31092587-31094587 NA NA NA
Expression of Target Genes for the Enhancer