About Enhancer
| Enhancer ID: | E_02495 |
| Species: | Mus musculus |
| Position : | chr16:92629000-92629500   |
| Year: | 2017 |
| Title: | A DNA Contact Map for the Mouse Runx1 Gene Identifies Novel Haematopoietic Enhancers |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | -- |
| PMID: | 29042628 |
| MONDO: | |
| Tissue: | Bone Marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | Mouse hematopoietic progenitor cell |
| CVCL ID: | |
| Cell Type: | hematopoietic progenitor cell |
| Cell Ontology ID: | CL:0000837 |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | ChIP-seq, DNase-seq |
| Low Throughput Method: | Transgenic Reporter Assay, RT-RT-qPCR |
About Target Gene
| Target gene : | Runx1 |
About TF
| TF name : | Erg |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Erg | ERK cascade ( FGF8 signaling (Mouse) ) | inoh | 17 |
| Erg | ERK cascade ( FGF8 signaling (Xenopus) ) | inoh | 17 |
| Erg | FGF8 signaling pathway(Mouse) ( FGF8 signaling (Mouse) ) | inoh | 20 |
| Erg | FGF8 signaling pathway(Xenopus) ( FGF8 signaling (Xenopus) ) | inoh | 18 |
| Erg | PDGF signaling pathway | panther | 113 |
| Erg | Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 | wikipathways | 153 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02491 | chr16:92629000-92629500 | Bone Marrow | hematopoietic progenitor cell | -- |
Expression of Target Genes for the Enhancer