Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02513
Species: Homo sapiens
Position : chr14:56245000-56285000
Year: 2018
Title: Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
PMID:  29348663
Cell Source: Endothelial Cells (ECs)
Cell Type: endothelial cell
Cell Ontology ID: CL:0000115
Experiment Type: TF-binding/chromatin assay; Chromatin interaction assay; Endogenous enhancer perturbation
High Throughput Method: ChIP-seq; Hi-C
Low Throughput Method: CRISPR-Cas9 targeted editing/deletion; ChIP-qPCR/ChIP; RT-qPCR/qPCR
About Target Gene
Target gene : LINC00520
About TF
TF name : KLF2
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
KLF2 Hs_White_fat_cell_differentiation_WP3946_90940 wikipathways 30
Enhancer Associated Network
Overlapping Enhancers (hg19) 1 found
Enhancer ID Position Tissue Cell Disease
E_02514 chr14:56245000-56285000 NA endothelial cell NA
Expression of Target Genes for the Enhancer