Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02531
Species: Mus musculus
Position : chrX:7826505-7830405
Year: 2011
Title: Nkx2-5 represses Gata1 gene expression and modulates its hematopoietic enhancer
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Disease
Disease Name: chronic myeloid leukemia
PMID:  21464046
MONDO: MONDO:0011998
Tissue: Bone marrow
Tissue Ontology ID: UBERON:0002371
Cell Source: K562
CVCL ID: CVCL_0004
Cell Type: chronic myeloid leukemia cell
Cell Ontology ID: CL:0001054
Experiment Type: Enhancer activity assay, TF binding assay
High Throughput Method:
Low Throughput Method: Luciferase Reporter Assay, Transgenic Reporter Assay
About Target Gene
Target gene : Gata1
About TF
TF name :
About Regulatory State
Regulatory State : Silenced
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 1 found
Enhancer ID Position Tissue Cell Disease
E_02532 chrX:7826505-7830405 Bone marrow embryonic stem cell --
Expression of Target Genes for the Enhancer