About Enhancer
| Enhancer ID: | E_02533 |
| Species: | Mus musculus |
| Position : | chr3:14768-15068   |
| Year: | 2011 |
| Title: | Tbx6-dependent Sox2 regulation determines neural vs mesodermal fate in axial stem cells |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 21326212 |
| MONDO: | |
| Tissue: | Embryo |
| Tissue Ontology ID: | UBERON:0000922 |
| Cell Source: | Axial stem cells |
| CVCL ID: | |
| Cell Type: | axial stem cell |
| Cell Ontology ID: | CL:0000037 |
| Experiment Type: | Enhancer activity assay, Functional perturbation assay |
| High Throughput Method: | |
| Low Throughput Method: | Transgenic Reporter Assay, CRISPR Knockout, EMSA, RT-RT-qPCR |
About Target Gene
| Target gene : | Sox2 |
About TF
| TF name : | Tbx6 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Tbx6 | Hs_Gene_regulatory_network_modelling_somitogenesis_WP2854_87527 | wikipathways | 12 |
| Tbx6 | Hs_Mesodermal_Commitment_Pathway_WP2857_87780 | wikipathways | 47 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer