About Enhancer
| Enhancer ID: | E_02537 |
| Species: | Mus musculus |
| Position : | chr9:107683970-107684232   |
| Year: | 2009 |
| Title: | Methyltransferase Set7/9 Maintains Transcription and Euchromatin Structure at Islet-Enriched Genes |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 18984737 |
| MONDO: | |
| Tissue: | Pancreas |
| Tissue Ontology ID: | UBERON:0001264 |
| Cell Source: | Islet |
| CVCL ID: | |
| Cell Type: | pancreatic islet cell |
| Cell Ontology ID: | CL:0000168 |
| Experiment Type: | Enhancer activity assay, TF binding assay |
| High Throughput Method: | |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, EMSA |
About Target Gene
| Target gene : | Setd7 |
About TF
| TF name : | Pdx1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Pdx1 | FOXA2 and FOXA3 transcription factor networks | pid | 45 |
| Pdx1 | Regulation of gene expression in beta cells | reactome | 17 |
| Pdx1 | Regulation of gene expression in early pancreatic precursor cells | reactome | 8 |
| Pdx1 | Type II diabetes mellitus | kegg | 44 |
| Pdx1 | Maturity onset diabetes of the young | kegg | 25 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer