About Enhancer
| Enhancer ID: | E_02559 |
| Species: | Mus musculus |
| Position : | chr8:105552148-105552347   |
| Year: | 2015 |
| Title: | PRDM16 enhances nuclear receptor-dependent transcription of the brown fat-specific Ucp1 gene through interactions with Mediator subunit MED1 |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 25644605 |
| MONDO: | |
| Tissue: | Embryo |
| Tissue Ontology ID: | UBERON:0000922 |
| Cell Source: | Mouse embryonic fibroblasts |
| CVCL ID: | CVCL_0003 |
| Cell Type: | mouse embryonic fibroblast |
| Cell Ontology ID: | CL:0000057 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay |
| High Throughput Method: | |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR, Western blot, Co-IP, In vitro transcription assay |
About Target Gene
| Target gene : | Ucp1 |
About TF
| TF name : | Prdm16 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Prdm16 | PKMTs methylate histone lysines | reactome | 64 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer