About Enhancer
| Enhancer ID: | E_02571 |
| Species: | Mus musculus |
| Position : | chr7:103826000-103826500   |
| Year: | 2011 |
| Title: | Cohesin Mediates Chromatin Interactions That Regulate Mammalian ??-globin Expression |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 21454523 |
| MONDO: | |
| Tissue: | Fetal liver |
| Tissue Ontology ID: | UBERON:0002107 |
| Cell Source: | MEL erythroleukemia cells |
| CVCL ID: | CVCL_2109 |
| Cell Type: | erythroid progenitor cell |
| Cell Ontology ID: | CL:0000038 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | |
| Low Throughput Method: | 3C, ChIP-loop, ChIP-RT-qPCR, siRNA Knockdown, RT-RT-qPCR |
About Target Gene
| Target gene : | Hbb-B1 |
About TF
| TF name : | Rad21 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Rad21 | Cohesin Loading onto Chromatin | reactome | 10 |
| Rad21 | Establishment of Sister Chromatid Cohesion | reactome | 11 |
| Rad21 | Meiotic synapsis | reactome | 76 |
| Rad21 | Resolution of Sister Chromatid Cohesion | reactome | 100 |
| Rad21 | Separation of Sister Chromatids | reactome | 163 |
| Rad21 | SUMOylation of DNA damage response and repair proteins | reactome | 76 |
| Rad21 | Cell cycle | kegg | 124 |
| Rad21 | Cell cycle - yeast | kegg | 66 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer